1,2-sulfanyl group migration as a driving force: new approach to pyrroles by reaction of allenic aldehydes with amines.
نویسندگان
چکیده
[reaction: see text] Acid-promoted reaction of sulfanyl group substituted allenic aldehyde with amine affords pyrrole derivatives in high yields. The neighboring group participation of the sulfanyl group is the driving force in this transformation.
منابع مشابه
Organocatalytic multicomponent synthesis of polysubstituted pyrroles from 1,2-diones, aldehydes and arylamines.
We have developed an organocatalyzed three-component reaction of 1,2-diones, aldehydes and arylamines, which provides an efficient approach to access polysubstituted pyrroles. In the catalysis of 4-methylbenzenesulfonic acid monohydrate, the reactions of a wide range of 1,2-diones, arylamines and aldehydes took place smoothly to generate the corresponding polysubstituted pyrroles in acceptable ...
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ورودعنوان ژورنال:
- Organic letters
دوره 9 8 شماره
صفحات -
تاریخ انتشار 2007